John Lowell (judge) (1824–1897), U.S. Federal judge and son of John Amory Lowell
Josephine Shaw Lowell (1843–1905), sister of American Civil War hero Robert Gould Shaw, first woman to hold a public office in New York City, and wife of Gen. Charles Russell Lowell
Maria White Lowell (1821–1853), poet, abolitionist, and wife of James Russell Lowell
Mike Lowell (born 1974), baseball player for the Boston Red Sox
Norman Lowell (born 1946), founder of the extreme-right Maltese political party, Imperium Europa
Percival Lowell (1855–1916), author, astronomer, founder of Lowell Observatory, and brother of Amy and Abbott Lawrence Lowell
Ralph Lowell (1890–1978), businessman, philanthorpist, and founding force behind Boston's WGBH public television
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